Steroids liver disease dogs

A very typical case of severe cholestasis due to anabolic steroid use.  Because the steroids were being used without medical supervision, the dose and actual duration of use of each preparation was unclear, but cholestasis usually arises within 4 to 12 weeks of starting a C-17 alkylated androgenic steroid.  The jaundice can be severe and prolonged and accompanied by severe pruritus and marked weight loss.  The serum enzymes are typically minimally elevated except for a short period immediately after stopping therapy.  The pattern of enzyme elevations can be hepatocellular, cholestatic or mixed.  Liver biopsy shows a “bland” cholestasis with minimal inflammation and hepatocellular necrosis.  Ma Huang has also been implicated in cases of drug induced liver injury, but is associated with an acute hepatocellular pattern of injury.

Hepatitis C causes chronic hepatitis. An infected individual may not recall any acute illness. Hepatitis C is spread by exposure to body fluids (needles from drug abusers, contaminated blood, and some forms of sexual contact). Chronic hepatitis C may lead to cirrhosis and liver cancer . At present, there is no vaccine against this virus. There is a recommendation to test all people born between 1945 and 1965 for Hepatitis C antibody to identify people who do not know that they have contracted the disease. Newer medications are now available to treat and potentially cure Hepatitis C.

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Calcinosis is a rare condition in dogs and is a side effect of high corticosteroid levels in the body; there is a bit of a double edged sword here where the balance between the calcinosis and the lungs needs to be evaluated. It may be worth speaking with an Oncologist to discuss the possible lung cancer and to try and make a definitive diagnosis of which specific cancer may be present, afterwards a treatment protocol with a lower dose of steroids along with other medications will manage the condition. Regards Dr Callum Turner DVM
http:///

Steroids liver disease dogs

steroids liver disease dogs

Calcinosis is a rare condition in dogs and is a side effect of high corticosteroid levels in the body; there is a bit of a double edged sword here where the balance between the calcinosis and the lungs needs to be evaluated. It may be worth speaking with an Oncologist to discuss the possible lung cancer and to try and make a definitive diagnosis of which specific cancer may be present, afterwards a treatment protocol with a lower dose of steroids along with other medications will manage the condition. Regards Dr Callum Turner DVM
http:///

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