It is important to note, however, that the use of testosterone supplementation does have associated side effects. One of the most notable is a decrease in the size and mass of the person’s testicles. Testosterone is created in our bodies, by cells in our testicles, as needed. Once exogenous testosterone is introduced into the body, the body detects the presence of this testosterone and, deeming the amount sufficient for the body’s needs, reduces the amount produced from the testicles. As the testicles produce less testosterone, the cells within the testicles degenerate in a process known as “atrophy.”
Doctor-patient articles related to symptoms and diagnosis:
Testicular atrophy is one such issue, although many of the studies suggesting it does cause shrinkage are relatively outdated — from the 1980s. Nevertheless, the majority of it suggests that smoking weed lowers testosterone levels, either directly or through precursor hormones; or causes testicular atrophy in monkeys and dogs. A study from 2012 revives this idea, and finds some evidence in men living in the Niger delta area of Nigeria. In that study, 75 men who smoked marijuana were also likely to have shrunken testicles, infertility, and even male breasts.