Ormone steroideo significato

"To mimic sex steroid hormone fluctuations occurring with aging, we exposed retinal pigment epithelial cells, ARPE-19, to acute, prolonged or chronic estradiol and progesterone challenges," says Carlo Astarita, PhD, University of Siena and co-author of the study. "We found that chronic estradiol treatment induces cell death of RPEs via necrosis, through mechanisms involving the subcellular localization of the retinoblastoma related protein pRb2/p130 and the extracellular plasminogen activator inhibitor type-2, PAI-2."

Ormone steroideo significato

ormone steroideo significato

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