Non-steroidal muscle building supplements

COX-2 inhibitors and gastroduodenal toxicity: Major clinical trials
COX-2 selective inhibitors: Adverse cardiovascular effects
Nonselective NSAIDs: Adverse cardiovascular effects
Nonselective NSAIDs: Overview of adverse effects
NSAIDs (including aspirin): Pathogenesis of gastroduodenal toxicity
NSAIDs (including aspirin): Primary prevention of gastroduodenal toxicity
NSAIDs (including aspirin): Role in prevention of colorectal cancer
NSAIDs (including aspirin): Secondary prevention of gastroduodenal toxicity
NSAIDs (including aspirin): Treatment of gastroduodenal toxicity
NSAIDs and acetaminophen: Effects on blood pressure and hypertension
NSAIDs: Acute kidney injury (acute renal failure)
NSAIDs: Adverse effects on the distal small bowel and colon
NSAIDs: Electrolyte complications
NSAIDs: Pharmacology and mechanism of action
NSAIDs: Therapeutic use and variability of response in adults
Overview of selective COX-2 inhibitors

Studies have shown that people who take anti-inflammatory painkillers have a small but significant increase in the risk of developing a heart attack  or stroke . Although it can occur in anybody, the risk is mainly in people already known to have cardiovascular problems such as angina or peripheral arterial disease , and in the elderly. Perhaps the highest risk is in people who have previously had a heart attack. For example, one research study looked at people who had previously had a heart attack. The results showed a marked increase in the rate of a second heart attack in people who were taking an anti-inflammatory compared to those who were not.

In the past several years, some newer medications have come on the market; these are commonly referred to as COX-2 inhibitors . Remember, all NSAIDs work against cyclooxygenase (COX). Traditional NSAIDs (. Ibuprofen, Motrin, Aleve) work against both COX-1 and COX-2. COX-1 and COX-2 are both types of cyclooxygenase enzymes that function in your body. The new medications (. Celebrex) work primarily against COX-2, and allow COX-1 to function normally. Because COX-1 is more important in producing the protective lining in your gut (gastric mucosa), these newer NSAIDs are believed to have less of a risk of causing stomach ulcers.

Non-steroidal muscle building supplements

non-steroidal muscle building supplements

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