Following the short-term treatment of patients with panic disorder in Studies 1 and 2 (see CLINICAL PHARMACOLOGY : Clinical Trials ), patients were gradually withdrawn during a 7-week downward-titration (discontinuance) period. Overall, the discontinuance period was associated with good tolerability and a very modest clinical deterioration, without evidence of a significant rebound phenomenon. However, there are not sufficient data from adequate and well-controlled long-term clonazepam studies in patients with panic disorder to accurately estimate the risks of withdrawal symptoms and dependence that may be associated with such use.
I believe there is a development link that is missed (at some point) when kids spend hours in front of a screen or texting. “Let’s pretend” is a game that requires imagination and if kids miss interacting with other kids pretending to be pirates searching for treasure or building a fort with cardboard boxes they will never know that they can make a difference. Working with other kids building a fort they learn social skills without realizing it. They learn to work together for a common goal. No computer screen can teach or help kids to make that connection.
Newer medications help reduce the time it takes to fall asleep. Some of these sleep-inducing drugs, which bind to the same receptors in the brain as do benzodiazepines, include Lunesta , Sonata , and Ambien . They are somewhat less likely than benzodiazepines to be habit-forming, but over time can still sometimes cause physical dependence. They can work quickly to increase drowsiness and sleep. Another sleep aid, called Rozerem , acts differently from other sleep medicines by affecting a brain hormone called melatonin, and is not habit-forming. Belsomra is another unique sleep aid that affects a brain chemical called orexin , and is not addictive or habit-forming.