Nasal steroids for allergies

We included 12 medium to high-quality studies with a total of 945 participants. No study documented hearing loss associated with OME prior to randomisation . The follow-up period was generally limited, with only one study of intranasal steroid reporting outcome data beyond six months. There was no evidence of benefit from steroid treatment ( oral or topical) in terms of hearing loss associated with OME. Pooled data using a fixed-effect model for OME resolution at short-term follow up (< 1 month) showed a significant effect of oral steroids compared to control ( RR ; 95% CI to ; Chi² , df = 2, P = ; I² = 27%). Oral steroids plus antibiotic also resulted in an improvement in OME resolution compared to placebo plus antibiotic at less than one month follow up, using a random-effects model ( RR ; 95% CI to ; five trials, 409 children). However, there was significant heterogeneity between studies ( P < , I² = 69%). There was no evidence of beneficial effect on OME resolution at greater than one month follow up with oral steroids (used alone or with antibiotics) or intranasal steroids (used alone or with antibiotics) at any follow-up period. There was also no evidence of benefit from steroid treatment ( oral or topical) in terms of symptoms.

Regarding diagnosis:

  • What is the cause of the deviated septum? Trauma? Birth defect?
  • If trauma-related, did additional injuries occur to the nose or surrounding area requiring additional treatment or correction, such as rhinoplasty?
  • Were other conditions noted or ruled out, including allergic rhinitis, mucosal edema, or irritation from long-term use of decongestant spray; or from cocaine abuse?
Regarding treatment:
  • How long were symptoms present prior to correction? How severe?
  • Have decongestants, antibiotics, or nasal inhaled steroids failed to satisfactorily treat individual?
  • If treated medically, was treatment palliative or curative?
  • Is septal surgery warranted?
  • Will additional treatment (surgical correction) be necessary in the future?
Regarding prognosis:
  • If surgical correction was required, what method was used? Septoplasty? Submucous resection?
  • Was successful correction accomplished? If not, what is being considered as future treatment? Rhinoplasty?
  • Do symptoms persist despite surgical correction?
Source: Medical Disability Advisor

Nasal steroids for allergies

nasal steroids for allergies

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