The black box warning on the . FDA-approved ciprofloxacin label warns of an increased risk of tendinitis and tendon rupture, especially in people who are older than 60 years, people who also use corticosteroids, and people with kidney, lung, or heart transplants. Tendon rupture can occur during therapy or even months after discontinuation of the medication.  A case-control study  performed using a UK medical care database found that fluoroquinolone use was associated with a -fold increase in tendon problems. The relative risk increased to in those over 60 years of age and to in those over the age of 60 who were also taking corticosteroids. Among the 46,766 quinolone users in the study, 38 (%) cases of Achilles tendon rupture were identified. A study performed using an Italian healthcare database reached qualitatively similar conclusions. 
All-in-one weight gainers take the guess work out of what supplements to use to maximise muscle growth and performance by combining all of the most essential nutrients required in one convenient shake. See More They are a blend of protein, carbohydrates and ergogenic aids which provide the necessary calories to build muscle as well as helping to enhance strength, endurance and recovery all-in-one weight gainer category is now arguably the second largest category in the sports nutrition market. All-in-one weight gainers are typically based on the same 2:1 ratio of protein to carbs as standard weight gainers. This ratio has been shown to be the most beneficial to muscle growth as it provides sufficient carbohydrates to load and replenish muscle glycogen which is the muscles main energy source, as well as ample amounts of protein to provide the amino acids required for muscular repair and growth.