Grapefruit juice oral steroids

My husband had a reoccurring fungus on his shins for about 3 years…weed-eating in shorts and flip-flops. Doctor gave him an antibiotic ointment, took a while to heal because it would itch like the dickens and he would scratch himself bloody at times. It would go away and come back repeatedly until a health food store owner recommended Nutribiotic’s brand of GSE to me. We haven’t seen the fungus since…that was 12 years ago.
At the same time my husband was treating his fungus, our oldest son (then just one year old) had a disturbing, red, raised dime sized rash appear on his leg that grew to quarter size. I feared it could be ringworm but never had it diagnosed. When nothing else worked, I began applying diluted GSE on it and it disappeared as well.
I know your article doesn’t deny the effectiveness of GSE, but I think in certain topical situations (we used to take it internally too), I’ll probably continue to use the bottle I have (Nutribiotic’s brand) because it is so fast acting and effective and requires so little product. One drop goes a long way.
I do plan on contacting the company, however, to ask questions, as well as voice my concerns about potentially harmful, hidden ingredients. Who knows, it may be our last bottle.
Thanks for all your research, Heather, and helping others to make informed decisions.

Administration advice :
-The IV formulation should be diluted prior to use and the infusion rate should not exceed 60 mg/min in adults.
-If given IM, limit the volume to 5 mL per site. Injections should be administered deeply into large muscles.

Storage requirements :
-The manufacturer product information should be consulted.

Reconstitution/preparation techniques :
-The manufacturer product information should be consulted.

General :
-If discontinuation is necessary, this drug should be withdrawn slowly to prevent seizures or status epilepticus.
-Dosing should be based on a patient's age, weight, and condition.
-Anticonvulsant activity is believed to be present at sub-hypnotic doses.

Monitoring :
-Blood pressure, respiration, and cardiac function during IV administration or IM (at hypnotic doses).
-Hematopoietic, renal and hepatic function periodically, especially during long-term therapy.
-Bone mineral density, especially during prolonged treatment.

Patient advice :
-Advise patients, and families/caregivers to monitor and report signs/symptoms of suicidality, and/or unusual behavior immediately to their healthcare provider (., agitation, irritability, anxiety, panic attacks, insomnia, hostility, aggressiveness, impulsivity, akathisia, hypomania/mania).
-Patients should be cautioned about performing activities requiring mental alertness, such as operating hazardous machinery or a motor vehicle, until they are reasonably certain that this drug does not adversely affect them.
-Patients should be told to avoid consuming alcohol while taking this drug.
-Instruct patients to immediately report any signs/symptoms of Stevens-Johnson syndrome, toxic epidermal necrolysis, hematological disease, or hypersensitivity reactions.
-Patients should be advised to report all concurrent prescription and nonprescription medications or herbal products they are taking.
-Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.

Research studies have shown that many drugs interact adversely with grapefruit. Certain compounds in the fruit called furanocoumarins may irreversibly inhibit cytochrome P450 3A4 isoenzymes (3A4) in the liver and intestinal wall. This enzyme inhibition decreases pre-systemic metabolism of some drugs taken up to 72 hours after eating this fruit and could adversely increase their levels within the blood. This resulting increase in drug levels might lead to serious adverse effects and toxicity. It is, therefore, strongly advised to consult your healthcare practitioner about consuming grapefruit juice if you are taking any pharmaceutical drugs.

Grapefruit juice oral steroids

grapefruit juice oral steroids


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